“Line-free lips are a sign of youth, beauty and sexuality,” says Marina Peredo, MD, a board-certified dermatologist and an associate clinical professor of dermatology at Mount Sinai Hospital in New York. “When lips age, they get thinner and develop wrinkles, which, in some cases can become very visible,” she says. Because people tend to focus on someone’s mouth as he or she talks, the lines on and around lips tend to age us the most.

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